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Translational & Clinical


Nationwide studies

Nationwide epidemiology and healthcare utilization of spine tumor patients in the adult Korean population, 2009–2012

Of 1600 primary spine tumors diagnosed from 2009 to 2012, 373 (23.3%) were malignant, and 1227 (76.7%) were nonmalignant.

The most common tumor type was neoplasm of spinal cord among primary malignant (C72.0, 51.5%) and primary nonmalignant (D33.4,
66.2%) spine tumors. Differences in primary malignant, primary nonmalignant, and metastatic spine tumor incidence by sex were significant (P ¼ .004, ,.001, and ,.001, respectively). The annual incidence rate of primary nonmalignant and metastatic spine tumors increased
significantly over the study period (P ¼ .005 and ,.001, respectively). Lung, liver/biliary, and breast were the most prevalent original tumor
sites for metastatic spine tumors. In 2011, average annual medical costs associated with treatment of primary malignant, primary nonmalignant, and metastatic tumors were US $15 223, $6502, and $16 038, respectively. Average annual hospital stay durations for primary
malignant, primary nonmalignant, and metastatic spine tumors in 2011 were 103.4, 61.7, and 79.6 days, respectively.

A Nation-Wide Epidemiological Study of Newly Diagnosed Primary Spine Tumor in the Adult Korean Population, 2009-2011

The incidence rate of a primary spine tumor increased with age, and the year of diagnosis (p≤0.0001). Average annual medical costs ranged from 1627 USD (pelvis & sacrum & coccyx tumors) to 6601 USD (spinal cord tumor) for primary nonmalignant spine tumor and from 12137 USD (spinal meningomas) to 20825 USD (pelvis & sacrum & coccyx tumors) for a primary malignant spine tumor. Overall survival rates for those with a primary malignant spine tumor were 87.0%, 75.3%, and 70.6% at 3, 12, and 24 months, respectively. The Cox regression model results showed that male sex, medicare insurance were significantly positive factors affecting survival after a diagnosis of primary malignant spine tumor.

A nationwide epidemiological study of newly diagnosed spine metastasis in the adult Korean population

The incidence rate of spine metastasis increased with age, year of diagnosis, and the number of comorbidities (p≤.0001). The 6 most prevalent primary tumor sites were lung, liver and biliary tract, breast, colon, stomach, and prostate. Of patients with the 6 most prevalent primary tumors, total average annual medical costs, including inpatient and outpatient services, ranged from 12,734

A Nationwide Study of Stereotactic Radiosurgery in a Newly Diagnosed Spine Metastasis Population

In 628 new patients, there were no significant differences between groups regarding gender, age, type of health insurance, and comorbidities. There were significant differences with regard to the medical costs (USD 23,276 vs. 18,458; p = 0.001) and the duration of hospital stay (101.3 vs. 86.5 days; p = 0.023). Median survival was significantly longer in the SRS group (p = 0.003).

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